Custom siRNA: Custom siRNA design
When designing siRNA, it is necessary to aim for both high gene-silencing activity and a low risk of off-target effects.
We provide a sequence-design service using our own literature-based machine-learning design method that is expected to give high gene-silencing activity.
- It can produce siRNA sequences that are optimal for RISC complex formation.
- It allows a search of all known genes of all species for siRNA targets.
- BLAST searching allows for the maximum suppression of off-target effects.
<Specifications of products>
- We offer all sequence information on the designed siRNA.
- After purification of the siRNA, we check its molecular weight by HPLC and MALDI-TOF mass spectrometry.
- The siRNA is supplied as a freeze-dried powder accompanied by a vial of nuclease-free water.
- The siRNA product is delivered within 10-14 business days.
- Depending on the sequence of the target gene, there are cases in which an siRNA sequence that shows gene silencing cannot be designed.
